产品货号：
Z16142
中文名称：
FOXO1抗体
英文名称：
Anti-FOXO1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FOXO1 Antibody |
| 指标别名 | FKH1;FKHR;forkhead box O1;Forkhead box protein O1;Forkhead box protein O1A;Forkhead in rhabdomyosarcoma;FOXO1;FOXO1A |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | FOXO1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | FOXO1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human FOXO1.The immunogen is located within the first 50 amino acids of FOXO1. |
| 计算分子量 | 70kDa |
| 成分 | FOXO1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | FOXO1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | FOXO1 antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures. |
| 背景资料 | FOXO1,also known as FKHR or ForkHead in Rhabdomyosarcoma,is a 70kDa protein which is a ubiquitously expressed member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus.FOXO transcription factors are key players of cell fate decisions,metabolism,stress resistance,tumor suppression and are regulated by growth factors,oxidative stress or nutrient deprivation.In insulin-responsive tissues,stress or nutrient abundance triggers phosphorylation by PKB/AKT,blocking nuclear translocation and activity.Genetic mutations involving FOXO1A are a cause of alveolar rhabdomyosarcoma (RMS2).Recent studies link the anti-tumor activity of FOXO1 and the process of autophagy. |
| Uniprot ID | Q12778 |
| 基因名全称 | Forkhead box O1 |
| 蛋白名全称 | Forkhead box O1 |
| 推荐稀释比 | FOXO1 antibody can be used for detection of FOXO1 by Western blot at 1μg/mL.Antibody can also be used for immunocytochemistry starting at 4μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunocytochemistry in human samples.All other applications and species not yet tested. |
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